Probe Library

Probe Library is a project created by the New and Jolliffe research groups at The University of Sydney. The project aims to provide a hub for information sharing between laboratories and research groups to most efficiently utilise resources.

Our Probes

BOL2

BOL2

This probe may be used to image lipids droplets in cells using confocal microscopy.

ReferenceAnalysis & Sensing 2024, 4, e202300049

BOL1

BOL1

This probe may be used to image lipids droplets in cells using confocal microscopy. 

ReferenceAnalysis & Sensing 2024, 4, e202300049

CyCu1

CyCu1

This probe may be used to image the labile copper pool within cells. A ratiometric response may be observed using fluorescence confocal microscopy.

Reference: ACS Sens. 2024, 9, 6, 2858–2868

PIID Probe

PIID

This probe may be used for the detection of cell-surface phosphatidylserine, a key marker of apoptosis, in live cells. The probe is amenable to time-lapse fluorescence imaging and flow cytometry, and unlike Annexin V is insensitive to low Ca(II) levels.

NpFR1 Probe

NpFR1

This probe may be used to indicate the redox state within cells, via confocal microscopy. The probe displays higher emission intensities under more oxidizing conditions.

Reference:
Chem. Commun., 2014, 50, 8181

NpFR2 Probe

NpFR2

This probe may be used to indicate the redox state within mitochondria, via confocal microscopy or flow cytometry. The probe displays higher emission intensities under more oxidizing conditions.

References:
Org. Biomol. Chem., 2015, 13, 6686

InCCu1 Probe

InCCu1

This probe may be used to image the labile iron pool within mitochondria. A ratiometric response may be observed using fluorescence confocal microscopy.

References:
Metallomics, 2016, 8 (9), 915

FlCFe1 Probe

FlCFe1

This probe may be used to image the labile iron pool within cells and tumour spheroids. A ratiometric response may be observed using fluorescence confocal microscopy.

Reference:
Metallomics, 2018, 10 (4), 553